The CD18 antibody (PE) from MyBioSource.com is a Rat Monoclonal antibody to Miscellaneous. This antibody recognizes Zebrafish/Fish antigen. The CD18 antibody (PE) has been validated for the following applications: Flow Cytometry, and Immunohistochemistry.
Description
Rat monoclonal CD18 antibody (PE)
Integrin beta-2 (CD18) is a protein that in humans is encoded by the ITGB2 gene. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. In humans lack of CD18 causes Leukocyte Adhesion Deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues